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Open Access Research

Different exercise protocols improve metabolic syndrome markers, tissue triglycerides content and antioxidant status in rats

José D Botezelli1*, Lucieli T Cambri1, Ana C Ghezzi1, Rodrigo A Dalia1, Pedro P M Scariot1, Carla Ribeiro1, Fabrício A Voltarelli2 and Maria AR Mello1

Author Affiliations

1 Physical Education Department, São Paulo State University - UNESP, 24-A Av. 1515, Rio Claro, Zip Code:13607-331, Brazil

2 Physical Education Department, Mato Grosso Federal University-UFMT, Brasilia Av. 1200, Cuiabá, Zip Code: 78550-000, Brazil

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Diabetology & Metabolic Syndrome 2011, 3:35  doi:10.1186/1758-5996-3-35

Published: 19 December 2011

Abstract

Background

An increase in the prevalence of obesity entails great expenditure for governments. Physical exercise is a powerful tool in the combat against obesity and obesity-associated diseases. This study sought to determine the effect of three different exercise protocols on metabolic syndrome and lipid peroxidation markers and the activity of antioxidant enzymes in adult Wistar rats (120 days old).

Methods

Animals were randomly divided into four groups: the control (C) group was kept sedentary throughout the study; the aerobic group (A) swam1 h per day, 5 days per week, at 80% lactate threshold intensity; the strength group (S) performed strength training with four series of 10 jumps, 5 days per week; and the Concurrent group (AS) was trained using the aerobic protocol three days per week and the strength protocol two days per week.

Results

Groups A and S exhibited a reduction in body weight compared to group C. All exercised animals showed a reduction in triglyceride concentrations in fatty tissues and the liver. Exercised animals also exhibited a reduction in lipid peroxidation markers (TBARS) and an increase in serum superoxide dismutase activity. Animals in group A had increased levels of liver catalase and superoxide dismutase activities.

Conclusions

We concluded that all physical activity protocols improved the antioxidant systems of the animals and decreased the storage of triglycerides in the investigated tissues.

Keywords:
Physical exercise; liver damage; oxidative stress; rats